{"id":214,"date":"2020-07-30T17:01:17","date_gmt":"2020-07-30T21:01:17","guid":{"rendered":"https:\/\/cib.udp.cl\/cms\/?post_type=laboratorio&#038;p=214"},"modified":"2025-05-27T13:15:20","modified_gmt":"2025-05-27T16:15:20","slug":"laboratorio-de-fisiopatologia-celular-y-cancer","status":"publish","type":"laboratorio","link":"https:\/\/cib.udp.cl\/en\/laboratorio\/laboratorio-de-fisiopatologia-celular-y-cancer\/","title":{"rendered":"Laboratory of Cellular Pathophysiology and Cancer"},"content":{"rendered":"<p>FICEC laboratory develops an investigation related to cellular communication and the integration of cellular signals in different pathological systems. The study focuses on the search for factors associated with obesity that can induce the appearance of a neoplasm or favor the development and progress of an established cancer, especially those cancers sensitive to sex hormones associated with female physiology. Specifically, the research is carried out using different experimental approaches in in-vitro, ex-vivo and in-vivo models for the development of hypotheses about different forms of communication between cells, either through soluble factors of different biochemical nature or through vesicular structures (called exosomes), which function as true molecular messages that are transmitted between different cells. These messages through exosomal vesicles can induce positive or negative effects (slow down or induce and aggravate a disease) depending on donnor cell that, recipient cell and cellular context of both cell type (physiological or pathological state). In addition, the research also includes the possible relationship between factors associated with reproductive failure and the development or progression of cancers in women. The study on factors associated with certain pathologies and its possible negative effects on other cell types in the same system, is relevant considering that the end point of this study is the search for new therapeutic targets that can prevent or control diseases of national interest.<\/p>","protected":false},"featured_media":1985,"template":"","class_list":["post-214","laboratorio","type-laboratorio","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/cib.udp.cl\/en\/wp-json\/wp\/v2\/laboratorio\/214","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cib.udp.cl\/en\/wp-json\/wp\/v2\/laboratorio"}],"about":[{"href":"https:\/\/cib.udp.cl\/en\/wp-json\/wp\/v2\/types\/laboratorio"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cib.udp.cl\/en\/wp-json\/wp\/v2\/media\/1985"}],"wp:attachment":[{"href":"https:\/\/cib.udp.cl\/en\/wp-json\/wp\/v2\/media?parent=214"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}