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Laboratory of Cell Signaling and Bioinformatics

Members

Daniel Bórquez

Associate Professor, Faculty

[email protected]

Projects

PROJECT

(Español) Diseño Computacional y evaluación in vitro de inhibidores de IRP1 como posibles fármacos para el tratamiento de la Enfermedad de Parkinson

Funding Source

Enlace UDP

2020-2021

PROJECT

(Español) Tratamiento farmacológico de la enfermedad de Parkinson con cumarinas multifuncionales. Prueba de concepto en modelos animales de la enfermedad

Funding Source

FONDEF IDeA

2018-2019

Publications

PUBLICATION

Iron regulatory protein 1: the deadly switch of ferroptosis

Journal

Neural Regeneration Research

2023

PUBLICATION

Expanded bioinformatic analysis of Oximouse dataset reveals key putative processes involved in brain aging and cognitive decline

Journal

Free Radical Biology and Medicine

2023

PUBLICATION

Iron, the endolysosomal system and neuroinflammation: a matter of balance

Journal

Neural Regeneration Research

2022

PUBLICATION

New Players in Neuronal Iron Homeostasis: Insights from CRISPRi Studies

Journal

Antioxidants (Basel)

2022

PUBLICATION

Iron Neurotoxicity in Parkinson’s Disease

Journal

Handbook of Neurotoxicity

2021

PUBLICATION

(Español) Inflaming the Brain with Iron

Journal

Antioxidants (Basel)

2021

PUBLICATION

The APP Intracellular Domain (AICD) Interactome: Connecting APP Physiological Functions and Alzheimer´s Disease Pathologic Features

Journal

Nova Science Publishers

2020

PUBLICATION

Dissecting the Role of Redox Signaling in Neuronal Development

Journal

Journal of neurochemistry

2016

PUBLICATION

Bioinformatics Approaches for Predicting Kinase–Substrate Relationships

Journal

IntechOpen

2016

PUBLICATION

Searching for Novel Cdk5 Substrates in Brain by Comparative Phosphoproteomics of Wild Type and Cdk5-/- Mice

Journal

Plos One

2014

PUBLICATION

Bioinformatic Survey for New Physiological Substrates of Cyclin-dependent Kinase 5

Journal

Genomics

2013

PUBLICATION

The Amyloidogenic Pathway Meets the Reelin Signaling Cascade: A Cytoskeleton Bridge Between Neurodevelopment and Neurodegeneration

Journal

IntechOpen

2013

PUBLICATION

The Amyloid Precursor Protein Intracellular domain-fe65 Multiprotein Complexes: A Challenge to the Amyloid Hypothesis for Alzheimer’s Disease?

Journal

International Journal of Alzheimer's disease

2012

PUBLICATION

Regulation of Cell Polarity by Controlled Proteolytic Systems

Journal

Biological research

2011

PUBLICATION

Iron Toxicity: A Critical Review on its Role in Parkinson’s Disease

Journal

Nova Science Publishers

2008