Encontrado en Noticias

Encontrado en CIB UDP

Encontrado en Proyectos

Encontrado en Publicaciones

Encontrado en Publicaciones

Nada ha sido encontrado

Functional genomics

Gene expression regulation and neurogenomics

The activation of genomic programs and their regulation are determinants of the construction of our systems and correspond to targets of pathologies. The integration of functional genomic interactions in time and anatomical space, together with information derived from environmental conditions, allows predicting susceptibility and establishing deep mechanisms of physiological control and interaction with other systems. In our laboratory we develop scale-free network analysis as a basic tool to understand the etiopathogenesis of different diseases, with emphasis on neurodevelopment and its integration with environmental conditions.

Related Publications

PUBLICATION

Rapid ovarian transcript changes during the onset of premature ovarian insufficiency

Journal

Reproduction and Fertility

2022

PUBLICATION

Letter to editor: Searching for health data harmonization: a pending task

Journal

Revista Médica de Chile

2022

PUBLICATION

The impact of gene expression analysis on evolving views on avian brain organization

Journal

Journal of Comparative Neurology

2013

PUBLICATION

Comparative aspects of subplate zone studied with gene expression in sauropsids and mammals

Journal

Cerebral Cortex

2011

PUBLICATION

Co-option of Signalling Mechanisms from Neural Induction to Telencephalic Patterning

Journal

Reviews in the Neurosciences

2007

PUBLICATION

Homology in Amniote Brain Evolution: The Rise of Molecular Evidence

Journal

Brain Behavior and Evolution

2018

PUBLICATION

From sauropsids to mammals and back: New approaches to comparative cortical development

Journal

Journal of Comparative Neurology

2016

PUBLICATION

Pallial patterning and the origin of the isocortex

Journal

Frontiers in Neuroscience

2015

PUBLICATION

Prenatal stress down-regulates Reelin expression by methylation of its promoter and induces adult behavioral impairments in rats

Journal

Plos One

2015

PUBLICATION

The DNMT1 associated lncRNA Dali is an epigenetic regulator of neural differentiation

Journal

eLIFE

2014

PUBLICATION

Things change – How comparative transcriptomics suggests the pallium has evolved at multiple levels of organization

Journal

Brain, Behavior and Evolution

2013

PUBLICATION

Adult pallium transcriptomes surprise in not reflecting predicted homologies across diverse chicken and mouse pallial sectors

Journal

Proceedings of the National Academy of Sciences, USA

2013

PUBLICATION

Maternal-fetal unit interactions and eutherian neocortical development and evolution

Journal

Frontiers in Neuroanatomy

2013

Related Projects

PROJECT

Cerebellum-Like Artificial Neural Networks bioinspired on cerebellum neural architecture at multiple levels of complexity (CLANN)

Funding Source

SticAmsud -ANID

2022-2025

PROJECT

Impact of the high n-6 polyunsaturated fatty acid intake and/or maternal obesity on neurodevelopment. Is there an essential contribution of dietary n-3 fatty acids?

Funding Source

Fondecyt

2022-2026

PROJECT

Hyperandrogenism during prenatal and pubertal development alters functional brain networks compromising social cognition in daughters of women with Polycystic Ovary Syndrome: a double hit hypothesis

Funding Source

Fondecyt

2021-2025

PROJECT

Maternal obesity influences placental fatty acid transport. Is there an impact on fatty acid metabolism in the fetal liver?

Funding Source

Fondecyt

2018-2022

PROJECT

Alterations in spermatozoa DNA methylation in sons of women with polycystic ovary syndrome (PCOS): a male intergenerational approach

Funding Source

Fondecyt

2020-2023

Related Academics

Heidy Kaune

Associate Professor, Faculty

Laboratory of Reproduction

Juan F. Montiel

Full Professor, Faculty, CIB Director

Laboratory of Integrative Neurosciences

Yasna Muñoz

PhD Student Laboratory of Integrative Neurosciences

Laboratory of Integrative Neurosciences

Vicente Ruiz

Collaborating Researcher Laboratory of Integrative Neurosciences

Laboratory of Integrative Neurosciences